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Home»News»Q&A: Insulin resistance and hypertrophy, stimulant metabolism, and BMR variability
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Q&A: Insulin resistance and hypertrophy, stimulant metabolism, and BMR variability

adminBy adminFebruary 8, 2024No Comments4 Mins Read
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Q&A: Insulin resistance and hypertrophy, stimulant metabolism, and BMR variability
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Time Stamps

00:00:00 – Podcast Updates

  • The Future of Stronger By Science

00:21:29 – Q&A Intro and “How do you go about researching a whole new subject?” (Q1 from Teo)

00:39:29 – “Does T2DM make hypertrophy impossible?” (Q2 from Jon) 

  • Should You Cut Before You Bulk?: How Body-Fat Levels Affect Your P-Ratio
  • Body-Fat and P-Ratios: A Rebuttal To The Rebuttal
  • Body-Fat and P-Ratios: A Rebuttal To The Rebuttal To The Rebuttal
  • For more direct data on diabetic populations: Beyond general resistance training. Hypertrophy versus muscular endurance training as therapeutic interventions in adults with type 2 diabetes mellitus: A systematic review and meta-analysis. Acosta-Manzano et al. (2020)
  • Another 2020 systematic review: A Systematic Review with Meta-Analysis of the Effect of Resistance Training on Whole-Body Muscle Growth in Healthy Adult Males. Benito et al. Average increase of about 1.51kg.
  • Metformin: optimism that it would help with hypertrophy: Metformin to Augment Strength Training Effective Response in Seniors (MASTERS): study protocol for a randomized controlled trial
  • But, that didn’t pan out. Didn’t stop hypertrophy altogether, but did seem to reduce it: Metformin blunts muscle hypertrophy in response to progressive resistance exercise training in older adults: A randomized, double-blind, placebo-controlled, multicenter trial: The MASTERS trial

00:55:18 – “Does getting a pump increase strength?” (Q3 from Alexander) 

  • Size vs. Strength: How Important is Muscle Growth For Strength Gains?
  • Biomechanical implications of skeletal muscle hypertrophy and atrophy: a musculoskeletal model

01:05:20 –  Stimulant metabolism (Q4 from Connor Smith)

01:17:40 – “How much can BMR vary between individuals?” (Q5 from Jon) 

  • Do People Really Have “Fast Metabolisms” or “Slow Metabolisms”?

01:29:35 – “Is it possible to taper down activity levels (steps) without reducing calories?” (Q6 from Angela) 

  • Constrained energy expenditure

01:41:10 – “How do you incorporate plyometrics and explosive training for jump height” (Q8 from trugor) 

01:54:29 – “Is there any research showing damage to the blood vessels or whatnot in the longer term due to the blood pressure increase, because of bracing/Valsalva maneuver?” (Q9 from No_Performer_8133)

  • Occupational heavy lifting and risk of ischemic heart disease and all-cause mortality
  • Occupational physical activity and cardiovascular disease in the United States
  • Relationship between cumulative exposure to occupational lifting throughout working life and risk of ischemic heart disease in men and women. The Copenhagen Aging and Midlife Biobank

02:00:51 – “How much isolation work is too much?” (Q10 from tompa01) 

02:10:05 – “Favorite and least favorite things I’ve cooked” (Q11 from Ali Shah) 

Recommended products and more from the SBS team 

  • Work with a Stronger By Science coach: Get personalized training and nutrition plans and ongoing support from one of our expert coaches.
  • Try MacroFactor for free: Use code SBS to get a 14-day free trial of our nutrition app MacroFactor. MacroFactor has the fastest food logger on the market and its smart nutrition coach adapts to your metabolism to keep you on track with your goals. Download it today on the App Store or Google Play.
  • Join the Research Spotlight newsletter: Our newsletter is the easiest way to stay up to date with the latest exercise and nutrition science.
  • Join the SBS Facebook group and Subreddit.
  • BulkSupplements: Next time you stock up on supplements, be sure to use the promo code “SBSPOD” (all caps) to get 5% off your entire order.
  • MASS Research Review: Subscribe to the MASS Research Review to get concise and applicable breakdowns of the latest strength, physique, and nutrition research – delivered monthly.
  • Send your Q&A questions to podcast@strongerbyscience.com

The post Q&A: Insulin resistance and hypertrophy, stimulant metabolism, and BMR variability appeared first on Stronger by Science.



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